Research Library / Article Summary
Where There is Smoke There is Fear—Impaired Contextual Inhibition of Conditioned Fear in Smokers
Plain-English AddictionTube research summary with source link, DOI, key finding, and recovery relevance.
Neuropsychopharmacology • 25 Jan 2017 • Research
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This article may help explain addiction science through research on nicotine, mental health. The source abstract begins by describing: “The odds-ratio of smoking is elevated in populations with neuropsychiatric diseases, in particular in the highly prevalent diagnoses of post-traumatic stress and anxiety disorders.”
Key finding: We propose that smokers have a deficit in integrating contextual signs of safety, which is a hallmark of post-traumatic stress and anxiety disorders.
Why this may help: This may help explain why addiction can involve brain, behavior, mental health, craving, relapse, or treatment factors rather than simple willpower alone. It should be read as research information, not personal medical advice.
This article may help explain addiction science through research on alcohol, cannabis, nicotine, mental health. The source abstract begins by describing: “Cannabis is used widely as a recreational drug, and its legalization is an ongoing issue in several countries.”
Key finding: Here, we review the current state of knowledge about such vulnerability factors, the variations in types of cannabis, and the relationship between these and cognition and addiction.
Nature Reviews Neuroscience • 07 Apr 2016 • Reviews
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This article may help explain addiction science through research on opioid, alcohol, cannabis, nicotine. The source abstract begins by describing: “Despite the benefits associated with longer buprenorphine treatment duration (i.e., >180 days) (BTD) for opioid use disorder (OUD), retention remains poor.”
Key finding: Longer BTD is associated with diagnoses of psychiatric and somatic conditions in the EHR, as is the genetic score for OUD, loneliness, problematic alcohol use, and externalizing disorders.
Translational Psychiatry • 10 Jan 2024 • Research
opioidalcoholcannabisnicotinegeneticsmental health
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This article may help explain addiction science through research on alcohol, nicotine, brain science, mental health. The source abstract begins by describing: “People affected by psychotic, depressive and developmental disorders are at a higher risk for alcohol and tobacco use.”
Key finding: Further understanding of these relationships may assist clinicians in the development of future approaches to improve symptoms and cognition among psychotic, depressive and developmental disorders.
Translational Psychiatry • 07 Aug 2024 • Research
alcoholnicotinebrain sciencemental health
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This article may help explain addiction science through research on cannabis, nicotine, mental health, treatment. The source abstract begins by describing: “Cannabis, a widely used psychoactive substance, can trigger acute cannabis-associated psychotic symptoms (CAPS) in people who use cannabis (PWUC).”
Key finding: In light of the movements towards legalization of recreational cannabis, more research should focus on the potential harms related to cannabis use, to educate PWUC and the public about risks related to its use.
Translational Psychiatry • 06 Sept 2022 • Research
cannabisnicotinemental healthtreatment
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This article may help explain addiction science through research on alcohol, nicotine, genetics, mental health. The source abstract begins by describing: “Observational studies suggest that physical activity can reduce the risk of mental health and substance use disorders.”
Key finding: Enhancing PA may be an effective intervention strategy to reduce depressive symptoms and addictive behaviours, while promoting sedentary or light physical activities may help to reduce the risk of anorexia in at-risk individuals.
Molecular Psychiatry • 21 Jul 2023 • Research
alcoholnicotinegeneticsmental healthtreatment
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