Research Library / Article Summary

The effect and neural changes underlying mindfulness meditation training in patients with comorbid internet gaming disorder and depression: A randomized clinical trial

Plain-English AddictionTube research summary with source link, DOI, key finding, and recovery relevance.

Translational Psychiatry • 18 Feb 2026 • Research

dopaminebrain sciencecravinggeneticsmental healthtreatment

Research focus

This article may help explain addiction science through research on dopamine, brain science, craving, genetics. The source abstract begins by describing: “Internet gaming disorder (IGD) has been recognized as a serious mental illness and is often accompanied by depression (IGD-D).”

Key finding: These phenomena were supported by the correlation between FC and behavioral as well as biochemical measures, suggesting that MM is a promising therapy for IGD-D.

Why this may help: This may help explain why addiction can involve brain, behavior, mental health, craving, relapse, or treatment factors rather than simple willpower alone. It should be read as research information, not personal medical advice.

Article details

Authors: Xuefeng Xu, Huabin Wang, Guang-Heng Dong

DOI: 10.1038/s41398-026-03837-6

Open access: Open Access

Open original source article

Related article summaries

PET imaging of FAAH in chronic Cannabis users: longitudinal assessment during short-term abstinence

This article may help explain addiction science through research on cannabis, brain science, withdrawal, craving. The source abstract begins by describing: “Cannabis withdrawal in cannabis use disorder (CUD) increase the risk of relapse and lacks effective treatments.”

Key finding: Increases in FAAH (%ΔFAAH whole-brain) were significantly associated with longer cannabis abstinence, greater baseline depression severity, and tendency to act without thinking ( p

Neuropsychopharmacology • 09 May 2026 • Research

cannabisbrain sciencewithdrawalcravingrelapsemental health

Read plain-English summary Open source

Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum

This article may help explain addiction science through research on alcohol, cannabis, brain science, withdrawal. The source abstract begins by describing: “Alcohol use disorder (AUD) remains a pervasive public health issue with limited effective treatments.”

Key finding: These findings indicate that chronic CBD administration attenuates both behavioral and neurobiological facets of alcohol dependence by modulating neuronal excitability and preventing neurodegeneration, supporting its therapeutic potential for AUD and providing mechanistic insights for future research.

Neuropsychopharmacology • 10 Jul 2025 • Research

alcoholcannabisbrain sciencewithdrawalrelapsegenetics

Read plain-English summary Open source

Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking

This article may help explain addiction science through research on cocaine, brain science, craving, relapse. The source abstract begins by describing: “Cocaine use disorder represents a public health crisis with no FDA-approved medications for its treatment.”

Key finding: These findings suggest that gut bacteria, via their metabolites, are key regulators of drug-seeking behaviors, positioning the microbiome as a potential translational research target.

Neuropsychopharmacology • 02 Aug 2023 • Research

cocainebrain sciencecravingrelapsemental healthtreatment

Read plain-English summary Open source

Deconstructing the neurobiology of cannabis use disorder

This article may help explain addiction science through research on cannabis, brain science, genetics, mental health. The source abstract begins by describing: “There have been dramatic changes worldwide in the attitudes toward and consumption of recreational and medical cannabis.”

Key finding: Here Ferland and Hurd discuss risk factors related to the development of CUD its neurobiological characteristics.

Nature Neuroscience • 06 Apr 2020 • Reviews

cannabisbrain sciencegeneticsmental healthtreatmentreview

Read plain-English summary Open source

Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking

This article may help explain addiction science through research on cocaine, dopamine, brain science, craving. The source abstract begins by describing: “The authors show that rostral ventral pallidum projections to the ventral tegmental area (VTA) are activated during cue-induced reinstatement of cocaine seeking, and DREADD inhibition of these projections blocks this behavior.”

Key finding: This double dissociation in ventral pallidum subregional roles in drug seeking is likely to be important for understanding the mesocorticolimbic circuits underlying reward seeking and addiction.

Nature Neuroscience • 02 Mar 2014 • Research

cocainedopaminebrain sciencecravingrelapsegenetics

Read plain-English summary Open source