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The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety

Plain-English AddictionTube research summary with source link, DOI, key finding, and recovery relevance.

Neuropsychopharmacology • 12 Nov 2019 • Research

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Research focus

This article may help explain addiction science through research on methamphetamine, craving, relapse, mental health. The source abstract begins by describing: “Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which there are no effective pharmacotherapies.”

Key finding: Using a translatable addiction model, these findings demonstrate the therapeutic efficacy of chronic oxytocin after METH self-administration and supports the clinical utility of oxytocin for METH addiction in both sexes.

Why this may help: This may help explain why addiction can involve brain, behavior, mental health, craving, relapse, or treatment factors rather than simple willpower alone. It should be read as research information, not personal medical advice.

Article details

Authors: Nicholas A. Everett, Sarah J. Baracz, Jennifer L. Cornish

DOI: 10.1038/s41386-019-0566-6

Open access: Not marked open access

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