Research Library / Article Summary
Virtual reality-based cue exposure therapy reduces psychological craving in men with methamphetamine use disorder: a randomized controlled trial
Plain-English AddictionTube research summary with source link, DOI, key finding, and recovery relevance.
Translational Psychiatry • 26 Aug 2025 • Research
methamphetaminecravingrelapsemental healthtreatment
Research focus
This article may help explain addiction science through research on methamphetamine, craving, relapse, mental health. The source abstract begins by describing: “Reducing psychological craving is critical for preventing relapse in methamphetamine use disorder (MUD).”
Key finding: Clinical trial number: This randomized controlled trial was registered with the Chinese Clinical Trial Registry (Code: ChiCTR1800020014).
Why this may help: This may help explain why addiction can involve brain, behavior, mental health, craving, relapse, or treatment factors rather than simple willpower alone. It should be read as research information, not personal medical advice.
This article may help explain addiction science through research on methamphetamine, craving, relapse, mental health. The source abstract begins by describing: “Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which there are no effective pharmacotherapies.”
Key finding: Using a translatable addiction model, these findings demonstrate the therapeutic efficacy of chronic oxytocin after METH self-administration and supports the clinical utility of oxytocin for METH addiction in both sexes.
Neuropsychopharmacology • 12 Nov 2019 • Research
methamphetaminecravingrelapsemental healthtreatmentanimal study
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This article may help explain addiction science through research on cannabis, brain science, withdrawal, craving. The source abstract begins by describing: “Cannabis withdrawal in cannabis use disorder (CUD) increase the risk of relapse and lacks effective treatments.”
Key finding: Increases in FAAH (%ΔFAAH whole-brain) were significantly associated with longer cannabis abstinence, greater baseline depression severity, and tendency to act without thinking ( p
Neuropsychopharmacology • 09 May 2026 • Research
cannabisbrain sciencewithdrawalcravingrelapsemental health
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This article may help explain addiction science through research on opioid, withdrawal, craving, relapse. The source abstract begins by describing: “Existing pharmacological treatment options for opioid use disorder (OUD) face challenges that limit their efficacy.”
Key finding: This review adopts a translational approach to achieve several aims: (1) to outline the fundamental theories of orexin system function and relate orexinergic dysfunction to the disordered motivation and withdrawal states that characterize OUD; (2) to provide an up-to-date evaluation of preclinical and clinical evidence bases supporting the efficacy of orexin receptor antagonism for the treatment of OUD; (3) to discuss key clinical considerations of repurposing DORAs for OUD treatment, including safety and side effects (i.e., respiratory depression, anhedonia, and risk for abuse); and (4) to highlight the ongoing clinical efforts to determine therapeutic efficacy and safety profiles of DORAs for use in OUD populations.
Translational Psychiatry • 24 Oct 2025 • Reviews
opioidwithdrawalcravingrelapsemental healthtreatment
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This article may help explain addiction science through research on cocaine, brain science, craving, relapse. The source abstract begins by describing: “Cocaine use disorder represents a public health crisis with no FDA-approved medications for its treatment.”
Key finding: These findings suggest that gut bacteria, via their metabolites, are key regulators of drug-seeking behaviors, positioning the microbiome as a potential translational research target.
Neuropsychopharmacology • 02 Aug 2023 • Research
cocainebrain sciencecravingrelapsemental healthtreatment
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This article may help explain addiction science through research on methamphetamine, brain science, relapse, mental health. The source abstract begins by describing: “Early life stress (ELS) is associated with perturbed neural development and augmented vulnerability to mental health disorders, including addiction.”
Key finding: Adolescent oxytocin treatment reverses some of the ELS effects on later-life psychopathology and vulnerability to addiction.
Neuropsychopharmacology • 17 May 2022 • Research
methamphetaminebrain sciencerelapsemental healthtreatmentanimal study
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