Research Library / Article Summary
Addiction should be treated, not penalized
Plain-English AddictionTube research summary with source link, DOI, key finding, and recovery relevance.
Neuropsychopharmacology • 17 Aug 2021 • Reviews
opioidalcoholcocainecannabistreatmentreview
Research focus
This article may help explain addiction science through research on opioid, alcohol, cocaine, cannabis. The source abstract begins by describing: “Mitchell O, Caudy MS.”
Why this may help: This may help explain why addiction can involve brain, behavior, mental health, craving, relapse, or treatment factors rather than simple willpower alone. It should be read as research information, not personal medical advice.
This article may help explain addiction science through research on alcohol, cannabis, nicotine, dopamine. The source abstract begins by describing: “In this Opinion article, Nutt and colleagues examine the history of and current evidence for the dopamine theory of addiction.”
Key finding: These observations have implications for understanding reward and treatment responses in various addictions.
Nature Reviews Neuroscience • 15 Apr 2015 • Reviews
alcoholcannabisnicotinedopaminebrain sciencetreatment
Read plain-English summary Open source
This article may help explain addiction science through research on opioid, alcohol, cannabis, nicotine. The source abstract begins by describing: “Despite the benefits associated with longer buprenorphine treatment duration (i.e., >180 days) (BTD) for opioid use disorder (OUD), retention remains poor.”
Key finding: Longer BTD is associated with diagnoses of psychiatric and somatic conditions in the EHR, as is the genetic score for OUD, loneliness, problematic alcohol use, and externalizing disorders.
Translational Psychiatry • 10 Jan 2024 • Research
opioidalcoholcannabisnicotinegeneticsmental health
Read plain-English summary Open source
This article may help explain addiction science through research on opioid, alcohol, cannabis, nicotine. The source abstract begins by describing: “Substance use disorders (SUDs, including alcohol, cannabis, opioids, and tobacco) represent significant public health challenges.”
Key finding: Lastly, using a real-world dataset, we identified seven SUD-shared genes targeting drugs that may be repurposed for treating SUDs, particularly in those suffering from comorbid SUDs.
Molecular Psychiatry • 07 Oct 2025 • Research
opioidalcoholcannabisnicotinebrain sciencegenetics
Read plain-English summary Open source
This article may help explain addiction science through research on opioid, alcohol, cocaine, methamphetamine. The source abstract begins by describing: “Polysubstance use disorders ( ≥ 2 substance use disorders (SUDs)) are associated with high morbidity and mortality.”
Key finding: The elevated prevalence of polysubstance use disorders associated with early initiation of substance use underscores the critical need for evidence-based strategies to prevent alcohol, cannabis, and nicotine consumption before age 21.
Molecular Psychiatry • 29 Apr 2026 • Research
opioidalcoholcocainemethamphetaminecannabisnicotine
Read plain-English summary Open source
This article may help explain addiction science through research on opioid, alcohol, cocaine, methamphetamine. The source abstract begins by describing: “Substance use disorders (SUDs) are common and costly conditions that are partially attributable to genetic factors.”
Key finding: Overall, the findings highlight similarities and differences in immunogenetic profiles of SUDs that may influence the prevalence and co-occurrence of problematic SUDs and may contribute to assessment of SUD risk of an individual on the basis of their HLA genetic makeup.
Scientific Reports • 26 May 2023 • Research
opioidalcoholcocainemethamphetaminecannabisbrain science
Read plain-English summary Open source